Breaking the degenerative triad: Microenvironment reprogramming biomaterials for intervertebral disc regeneration.

Bioactive materials · 2026-10-23 · 综述

Intervertebral disc degeneration (IVDD) represents a leading cause of chronic low back pain worldwide, imposing considerable public health and socioeconomic burdens. Current clinical interventions remain largely palliative, unable to reverse the progressive pathological cascade. This cascade is driven by a core self-amplifying triad of oxidative stress, chronic inflammation, and nutrient deprivation within the unique…

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Zhao X, Han X, Hu Z 等

本文摘自《每日前沿研究简报 · 2026-11-06》「发育·再生·干细胞」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。