Molecular dynamics of α-hairpin motif in globular proteins: hydrophobic factor restricts the mobility of the peptide cha

Journal of biomolecular structure & dynamics · 2026-11-03 · 期刊论文

Molecular dynamics of the α-helical hairpin structural motifs in five selected globular proteins were considered. The dynamics of each polypeptide chain were investigated on four independent trajectories with total time of 400 ns. A decrease in the dynamic mobility of α-helical hairpins was clearly observed in the regions containing certain amino acid residues. And that phenomena depends on the contacts of non-polar …

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Chirgadze YN, Kharkina EA, Likhachev IV 等

本文摘自《每日前沿研究简报 · 2026-11-06》「化学信息 / 药物发现」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。