Self-extending DNA recording with stochastic and programmed writing

bioRxiv 预印本 · 2026-10-23 · 预印本

Recording cellular histories requires continued information accumulation while retaining earlier records. Infinite Printer couples DNA self-extension to regeneration of a writable terminal context. A single self-targeting prime-editing guide directs repeat extension, while base editing diversifies the accessible sequence in situ. A separate configuration uses auxiliary guides for specified payload writing. After thre…

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Zhang, Z., Li, Y., Peng, Y. 等

本文摘自《每日前沿研究简报 · 2026-10-25》「生物信息 / 组学（单细胞·差异表达）」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。